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Management of acetaminophen and ibuprofen toxicoses in dogs and cats

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

10.1016/j.ymben.2015.05.004 8 DatsenkoK

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In addition, in agreement with the long-range effects observed above, the multiple phosphorylations promoted more stable electrostatic interactions in the N-terminal region of OPTN, where E163 and K167 also participated in salt bridges, and pS174 contributed to strengthening the interaction with K49 ( Table S3, Figure 4B-D )